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| Antigenic Specificity | Poly (ADP-Ribose) Polymerase 1 (PARP1) (aa 215-525) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | unconjugated |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Immunohistochemistry (IHC),Immunoprecipitation (IP),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production. |
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| Immunogen | Recombinant mouse PARP-1 [ARTD1] (aa 215-525). |
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| Other Names | BEST:LD21673|CG17685|CG17696|CG17718|CG40411|D.PARP|Dm.pARTa|Dmel\\CG40411|LD21673.3prime|PARP|PARP-1|PARP1|dPARP|parp|ADPRT|ADPRT 1|ADPRT1|ARTD1|PPOL|pADPRT-1|Adprt|Parp-1|adprt1|padprt-1|ppol|5830444G22Rik|AI893648|Adprp|Adprt1|C80510|parp-1|sPARP-1 |
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| Gene, Accession # | Gene ID: 142,11545 |
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| Catalog # | ABIN2745551 |
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| Price | |
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| Order / More Info | Poly (ADP-Ribose) Polymerase 1 (PARP1) (aa 215-525) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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