| 产品详情 |
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| Product Name | Egl Nine Homolog 3 (C. Elegans) (EGLN3) peptide |
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| Description | EGLN3 catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. It hydroxylates HIF-1 alpha at 'Pro-564', and HIF-2 alpha. EGLN3 functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. It may play a role in cell growth regulation in muscle cells and in apoptosis in neuronal tissue. EGLN3 promotes cell death through a caspase-dependent mechanism. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | zgc:77019|wu:fj78a08|EGLN3|phd3|PHD-3|PHD3|SM-20|2610021G09Rik|AI505553|AI648162|Hif-p4h-3|Phd3|HIFP4H3|HIFPH3 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN938515 |
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| Price | |
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| Order / More Info | Egl Nine Homolog 3 (C. Elegans) (EGLN3) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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