| 产品详情 |
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| Product Name | Recombinant Human Polypyrimidine tract-binding protein 1 (PTBP1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 63.1kDa. Full Length of Isoform: 1-557aa. N-terminal 10xHis-tagged. Homo sapiens (Human). Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site and stimulates the IRES-mediated translation. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | 57 kDa RNA-binding protein PPTB-1 (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) (PTB) (PTB) |
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| Gene, Accession, CAS # | PTBP1, UniProt: P26599 |
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| Catalog # | RPC23845 |
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| Order / More Info | Recombinant Human Polypyrimidine tract-binding protein 1 (PTBP1) from BIOMATIK |
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| Product Specific References | n/a |
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