| 产品详情 |
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| Product Name | GRI-977143 |
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| Description | An LPA2 receptor agonist (EC50 = 3.3 µM in LPA2-transfected RH7777 cells); selective for LPA2, having no activity at LPA1, LPA3, LPA4, and LPA5 at concentrations up to 10 µM; increases growth and reduces caspase-3 and -7 activation in LPA2-transduced MEF fibroblasts; increases MM1 rat hepatoma cell invasion and inhibits apoptosis of IEC-6 cells induced by TNF-α, doxorubicin, or serum withdrawal; rescues apoptotic cells from γ-irradiation-induced injury in vitro and in vivo |
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| Size | 10 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | LPA-2 GRI977143 MM 1IEC6 TNFα |
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| Gene, Accession, CAS # | CAS: 325850-81-5 |
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| Catalog # | 21900-10 |
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| Order / More Info | GRI-977143 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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