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| Product Name | Recombinant Mouse Peroxisome proliferator-activated receptor gamma (Pparg) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 73.6kDa. Full Length of Isoform 2: 1-505aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Nuclear receptor subfamily 1 group C member 3 |
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| Gene, Accession, CAS # | Pparg, UniProt: P37238 |
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| Catalog # | RPC21845 |
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| Order / More Info | Recombinant Mouse Peroxisome proliferator-activated receptor gamma (Pparg) from BIOMATIK |
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| Product Specific References | n/a |
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