产品详情 |
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Antigenic Specificity | NAD(P)H Dehydrogenase, Quinone 1 (NQO1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoprotein that catalyzes the two-electron reduction of quinones and their derivatives . This enzyme protects cells against redox cycling and oxidative stress . The expression of NQO1 is increased in liver, colon and breast tumors and non-small cell lung cancer (NSCLC) compared with the normal tissues . Moreover, expression levels are also elevated in developing tumors, suggesting a role for NQ01 in the prevention of tumor development . Studies on NQO1 knockout mice suggest that the lack of NQO1 enzymatic activity changes intracellular redox states resulting in a reduction in apoptosis, which in turns leads to myeloid hyperplasia of bone marrow . Synonyms: DHQU, DIA4, DTD, NMOR1, NMORI, QR1 |
Immunogen | A synthetic peptide of human NQO1 |
Other Names | zgc:77191|wu:fb63c10|nqo1|DHQU|DIA4|DTD|NMOR1|NMORI|QR1|Dia4|AV001255|Dtd|Nmo-1|Nmo1|Nmor1|Ox-1|Ox1|Qr1|NADPH-d |
Gene, Accession # | Gene ID: 1728,18104,24314 |
Catalog # | ABIN1683827 |
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Order / More Info | NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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