| 产品详情 |
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| Antigenic Specificity | TSC2 (pS1387) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | IF/ICC, DB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mutations in TSC2 lead to tuberous sclerosis complex. The protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. This TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1387 of human TSC2. |
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| Immunogen | Human TSC2 (phospho-Ser1387). |
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| Other Names | TSC2; LAM; Tuberous sclerosis 2 protein; Tuberous sclerosis 2; TSC4; Tuberin |
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| Gene, Accession # | Accession: NP_000539.2, NP_001070651.1, NP_001107854.1, SwissProt: P49815 |
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| Catalog # | abx031950 |
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| Price | |
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| Order / More Info | TSC2 (pS1387) Antibody from ABBEXA |
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| Product Specific References | n/a |
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