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Antigenic Specificity | TSC1 (pS1141) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | DB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity). This rat TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1141 of rat TSC1. |
Immunogen | Rat TSC1 (phospho-Ser1141). |
Other Names | TSC1; KIAA0243; TSC; Hamartin; Tuberous sclerosis 1 protein; LAM; MGC86987 |
Gene, Accession # | SwissProt: Q9Z136 |
Catalog # | abx032237 |
Price | |
Order / More Info | TSC1 (pS1141) Antibody from ABBEXA |
Product Specific References | n/a |