| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | MCM3 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, monkey |
|---|
| Isotype | n/a |
|---|
| Format | affinity purified |
|---|
| Size | 50 µl, 100 µl, 200 µl |
|---|
| Concentration | > 1 mg/ml |
|---|
| Applications | WB, IHC, IF/ICC. RUO |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | MCM3 Antibody is a Rabbit Polyclonal antibody against MCM3. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene. |
|---|
| Immunogen | Recombinant protein of human MCM3. |
|---|
| Other Names | DNA polymerase alpha holoenzyme-associated protein P1; P1-MCM3; RLF subunit beta; p102; MCM3; DNA replication licensing factor MCM3; HCC5; MGC1157; P1.h; RLFB |
|---|
| Gene, Accession # | MCM3, Gene ID: 4172, SwissProt: P25205 |
|---|
| Catalog # | abx000983 |
|---|
| Price | |
|---|
| Order / More Info | MCM3 Antibody from ABBEXA |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|