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| Antigenic Specificity | Caveolin 1, Caveolae Protein, 22kDa (CAV1) (aa 164-178), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunocytochemistry (ICC),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CAV1, Caveolin-1, is a protein that in humans is encoded by the CAV1 gene. The CAV1 gene is mapped to 7q31.2. The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms(alpha and beta) are encoded by a single transcript from this gene. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Caveolin-1(164-178aa GKIFSNVRINLQKEI), different from the related rat and mouse sequences by three amino acids. |
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| Other Names | fc07c04|wu:fc07c04|Cav-1|bscl3|cav1|cav1a|cgl3|vip21|cav1b|caveolin-1|cav|mstp085|Caveolin-1|CAV1|cav-1|Cav|caveolin 1|BSCL3|CGL3|MSTP085|PPH3|VIP21 |
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| Gene, Accession # | Gene ID: 857,25404 |
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| Catalog # | ABIN1673023 |
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| Price | |
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| Order / More Info | Caveolin 1, Caveolae Protein, 22kDa (CAV1) (aa 164-178), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 17178917, 9717814, 11358800 |
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