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Antigenic Specificity | Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The aldehyde dehydrogenase family is a large group of enzymes that oxidize aldehydes formed through metabolic processes to their carboxylic acids. ALDH1A1 is a liver cytosolic isoform of acetaldehyde dehydrogenase and is involved in the major pathway of alcohol metabolism along with alcohol dehydrogenase. ALDH1A1 is also known as retinal dehydrogenase 1 and is involved in retinol metabolism, converting retinol to retinoic acid. Recent studies suggest that control of retinoid signaling through ALDH1A1 may influence hematopoietic stem cell differentiation. There has been recent interest in ALDH1 isoforms as predictive biomarkers in disease. Several studies have suggested that ALDH1A1 is a potential marker for cancer stem cells and chemoresistance in several tumor types, such as melanoma , lung cancer , glioblastoma.Synonyms: ALDC, ALDH-E1, ALDH1, ALDH11, MGC2318, PUMB1, RALDH1 |
Immunogen | Recombinant protein of human ALDH1A1 |
Other Names | AL1A1|aldc|aldh-e1|aldh1|aldh11|pumb1|raldh1|ALDH1A1|ALDC|ALDH-E1|ALDH1|ALDH11|PUMB1|RALDH1|Ahd2|Aldh1|Aldh2|GGADHR|ALDDH|Ahd-2|Aldh1a2|E1|Raldh1 |
Gene, Accession # | Gene ID: 216,11668,24188 |
Catalog # | ABIN1512562 |
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Order / More Info | Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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