| 产品详情 |
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| Product Name | MARK/Par-1 Activity Inhibitor, 39621 |
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| Description | Purity ~98% (HPLC). A cell-permeable dihydropyrazinyl-thioacetamide that acts as an ATP-competitive MARK-selective inhibitor (IC50=3.6uM; [ATP]=100uM). Shown to effectively block primary rat cortical neuron axon growth (5.7um/hr vs 32.5um/hr with or without 20uM inhibitor) and prevent MARK2 overexpression-induced Tau Ser262 phosphorylation and cytotoxicity in CHO cells (10uM). Formula: C21H21N3O3S Molecular Weight: 395.5 Solubility: DMSO (100mg/ml clear, yellow solution) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MARK/Par-1 Activity Inhibitor, 39621 (N-(2,5-Dimethylphenyl)-2-(4-(4-methoxyphenyl)-3-oxo-3,4-dihydropyrazin-2-ylthio)acetamide, Microtubule Affinity Regulating Kinase Inhibitor, MAP Affinity Regulating Kinase Inhibitor, PAR1 Inhibitor) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217532 |
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| Price | |
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| Order / More Info | MARK/Par-1 Activity Inhibitor, 39621 from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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