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| Product Name | Recombinant Human Interleukin-29 (IL29), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 36kDa. Partial: 21-200aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagent leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Cytokine Zcyto21Interleukin-29; IL-29 |
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| Gene, Accession, CAS # | IL29, UniProt: Q8IU54 |
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| Catalog # | RPC23293 |
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| Order / More Info | Recombinant Human Interleukin-29 (IL29), partial from BIOMATIK |
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| Product Specific References | n/a |
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