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| Product Name | Recombinant Macaca mulatta CD40 ligand (CD40LG), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 28.5kDa. Extracellular Domain: 44-261aa. N-terminal 6xHis-tagged. Macaca mulatta (Rhesus macaque). Cytokine that binds to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in conjunction with the TCR/CD3 ligation and CD28 costimulation. Induces the activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells. Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL4. Involved in immunoglobulin class switching. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Tumor necrosis factor ligand superfamily member 5; CD_antigen: CD154 |
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| Gene, Accession, CAS # | CD40LG, UniProt: P63304 |
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| Catalog # | RPC21055 |
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| Order / More Info | Recombinant Macaca mulatta CD40 ligand (CD40LG), partial from BIOMATIK |
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| Product Specific References | n/a |
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