| 产品详情 |
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| Product Name | Human SOD Protein (Active) |
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| Description | MW: 16 kDa. Human SOD Protein (Active) is an active recombinant protein from E. Coli. Superoxide dismutases (SOD) are enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. Thus, they are an important antioxidant defense in nearly all cells exposed to oxygen. Several common forms of SOD exist: they are proteins cofactored with copper and zinc, or manganese, iron, or nickel. Thus, there are three major families of superoxide dismutase, depending on the metal cofactor: Cu/Zn (which binds both copper and zinc), Fe and Mn types (which bind either iron or manganese), and the Ni type, which binds nickel. Three forms of superoxide dismutase are present in humans, in all other mammals, and most chordates. SOD1 is located in the cytoplasm, SOD2 in the mitochondria, and SOD3 is extracellular. Mutations in the first SOD enzyme (SOD1) can cause familial amyotrophic lateral sclerosis (ALS, a form of motor neuron disease). The other two isoforms of SOD have not been linked to any human diseases, however, in mice inactivation of SOD2 causes perinatal lethality and inactivation of SOD1 causes hepatocellular carcinoma. |
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| Size | 100 µg, 1 mg, 2 mg |
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| Concentration | n/a |
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| Applications | SDS-PAGE. RUO |
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| Other Names | Recombinant human SOD protein; Human recombinant SOD protein; SOD protein; SOD recombinant protein; human SOD recombinant protein; SOD human recombinant protein; SOD protein; active; SOD active protein |
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| Gene, Accession, CAS # | Gene ID: 6647, SwissProt: P00441 |
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| Catalog # | abx060221 |
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| Order / More Info | Human SOD Protein (Active) from ABBEXA |
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| Product Specific References | n/a |
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