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| Product Name | Recombinant Human Protein CYR61 protein (CYR61) (Active) |
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| Description | Purity > 95% as determined by SDS-PAGE and HPLC. MW: 39.4kDa. Full Length of Mature Protein: 25-381aa. tag-Free. Homo sapiens (Human). Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. {ECO:0000269|PubMed:11584015}. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CCN family member 1, Insulin-like growth factor-binding protein 10, IBP-10, IGF-binding protein 10, IGFBP-10 |
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| Gene, Accession, CAS # | CYR61,CCN1,GIG1,IGFBP10, UniProt: O00622 |
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| Catalog # | RPC26687 |
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| Order / More Info | Recombinant Human Protein CYR61 protein (CYR61) (Active) from BIOMATIK |
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| Product Specific References | n/a |
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