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| Product Name | Recombinant Human Protein CYR61 (CYR61) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 55.4kDa. Full Length of Mature Protein: 25-381aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-v/beta-5 and cell proliferation through integrin alpha-v/beta-3. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | CCN family member 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10; IGFBP-10; Protein GIG1 |
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| Gene, Accession, CAS # | CYR61, UniProt: O00622 |
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| Catalog # | RPC21185 |
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| Order / More Info | Recombinant Human Protein CYR61 (CYR61) from BIOMATIK |
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| Product Specific References | n/a |
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