| 产品详情 |
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| Product Name | Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) peptide |
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| Description | Lrp8 is the cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | LRP8|APOER2|HSZ75190|LRP-8|MCI1|4932703M08Rik|AA921429|AI848122|ApoER2|Lr8b|LR8B |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN936592 |
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| Order / More Info | Low Density Lipoprotein Receptor-Related Protein 8, Apolipoprotein E Receptor (LRP8) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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