| 产品详情 |
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| Product Name | Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His tag) |
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| Description | Low-Density Lipoprotein Receptor (LDLR) is a transmembrane glycoprotein that plays a critical role in cholesterol homeostasis. LDLR mediates blood cholesterol level by interacting with lipoprotein particles like LDL and VLDL. The extracellular domain of LDLR contains LDL receptor type A (ligand-binding) modules (LA repeats), epidermal growth factor-like modules, and LY repeats containing the YWTD consensus motif that are important in binding and releasing of ApoB-100 and ApoE in lipoprotein particles. The C terminal domain of LDLR inside the cell is required for the receptor internalization. Loss of function mutations in the LDLR gene causes Familial Hypercholesterolemia (FH). Synonyms: Low-density lipoprotein receptor9(LDL receptor for short), is a single-pass type I membrane protein which belongs to the LDLR family. |
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| Size | 500 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | FH|FHC|LDLCQ2|Hlb301|LDLRA|LDLA |
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| Gene, Accession, CAS # | Gene ID: 3949 |
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| Catalog # | ABIN2115370 |
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| Order / More Info | Low Density Lipoprotein Receptor (LDLR) (AA 22-788) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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