产品详情 |
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Antigenic Specificity | Forkhead Box P3 (FOXP3) (aa 321-337), (Middle Region) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | FOXP3(forkhead box P3) is a protein involved in immune system responses. The human FOXP3 genes contain 11 coding exons. Exon-intron boundaries are identical across the coding regions of the mouse and human genes. By genomic sequence analysis, the FOXP3 gene maps to the p arm of the X chromosome(specifically, Xp11.23). A member of the FOX protein family, FOXP3 appears to function as a master regulator in the development and function of regulatory T cells. While the precise control mechanism has not yet been established, FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. |
Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human FOXP3(321-337aa FPEFLHNMDYFKFHNMR), different from the related mouse sequence by two amino acids. |
Other Names | foxp3|FOXP3|AIID|DIETER|IPEX|PIDX|XPID|JM2|scurfin|sf|RGD1562112 |
Gene, Accession # | Gene ID: 50943 |
Catalog # | ABIN1673051 |
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Order / More Info | Forkhead Box P3 (FOXP3) (aa 321-337), (Middle Region) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 23098499, 22749378, 17182968, 24289115, 16211090, 11137993, 15851684 |
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