| 产品详情 |
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| Product Name | GAD1-iso1, 1-594aa, Human, His tag, E.coli (Denatured) |
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| Description | Purity: > 80% by SDS - PAGE Format: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol. This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This protein may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Recombinant human GAD1 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Glutamate decarboxylase 1, CPSQ1, GAD, SCP |
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| Gene, Accession, CAS # | NP 000808 |
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| Catalog # | ATGP2838 |
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| Price | |
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| Order / More Info | GAD1-iso1, 1-594aa, Human, His tag, E.coli (Denatured) from ATGen |
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| Product Specific References | n/a |
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