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Product Name | Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 34-240) protein (His tag) |
Description | Hepatocyte Cell Adhesion Molecule (HEPACAM) is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. HEPACAM includes a signal sequence (amino acid 1-33), an extracellular region (amino acid 34-240) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (amino acid 241-261), and a cytoplasmic domain (amino acid 262 - 416). The cytoplasmic domain plays an important role in regulation of cell-matrix adhesion and cell motility. HEPACAM acts as a homodimer and dimer formation occurs predominantly through cis interactions on the cell surface. HEPACAM is involved in cell motility and cell-matrix interactions. The expression of this gene is down-regulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene.Alternative Names: Hepatocyte Cell Adhesion Molecule, Protein HepaCAM, HEPACAM |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | GlialCAM|MLC2A|MLC2B|2900042E01Rik|Hepn1 |
Gene, Accession, CAS # | Gene ID: 220296 |
Catalog # | ABIN1096816 |
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Order / More Info | Hepatic and Glial Cell Adhesion Molecule (HEPACAM) (AA 34-240) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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