产品详情 |
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Antigenic Specificity | E Cadherin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB, FCM. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CDH1 is a classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This E Cadherin (CDH1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 833-862 amino acids from the C-terminal region of human E Cadherin (CDH1). |
Immunogen | Human E Cadherin. |
Other Names | CDH1; CDHE; UVO; E-Cad/CTF3; Cadherin-1; CAM 120/80; Epithelial cadherin; Uvomorulin; CD324; E-Cad/CTF1; E-Cad/CTF2; E-cadherin; E Cadherin |
Gene, Accession # | SwissProt: P12830 |
Catalog # | abx028301 |
Price | |
Order / More Info | E Cadherin Antibody from ABBEXA |
Product Specific References | n/a |
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