| 产品详情 |
| Edit |   |
|---|
| Product Name | Ciliary Neurotrophic Factor (CNTF) (AA 2-200) (Active) protein |
|---|
| Description | Ciliary Neurotrophic Factor (CNTF) is a cytokine belonging to the Interleukin 6 (IL-6) family, which also includes IL-6, Oncostatin M, Leukemia Inhibitory Factor (LIF), and Cardiotrophin-1. Structurally, CNTF resembles a four-helix bundle composition, similar to the other members of the IL-6 family. The receptor for CNTF is composed of three parts: a gp130-like subunit common in the IL-6 receptor family, a LIF Receptor beta subunit, and a CNTF specific alpha receptor subunit. Upon binding to the CNTF, the beta subunit of the CNTF receptor will undergo tyrosine phosphorylation, and activate the intracellular JAK/STAT pathway. The main function of CNTF in vivo is to promote the differentiation and survival of a variety of neurons and glial cells, including sympathetic precursor cells and spinal motor neurons.Recombinant human Ciliary Neurotrophic Factor (rhCNTF) produced in E. coli is a single non-glycosylated polypeptide chain containing 199 amino acids. A fully biologically active molecule, rhCNTF has a molecular mass of 22.8 kDa analyzed by reducing SDS-PAGE. Synonyms: Ciliary Neurotrophic Factor |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | CNTF|HCNTF|AI429687|GPA |
|---|
| Gene, Accession, CAS # | Gene ID: 1270 |
|---|
| Catalog # | ABIN2017716 |
|---|
| Price | |
|---|
| Order / More Info | Ciliary Neurotrophic Factor (CNTF) (AA 2-200) (Active) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|