产品详情 |
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Antigenic Specificity | TP53 (pS315) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TP53 (pS315) Antibody is a Rabbit Polyclonal antibody against TP53 (pS315). This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). |
Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S315 of human TP53. |
Other Names | bb; p44; p53; Tp53; BCC7; LFS1; TRP53; FLJ92943; Cellular tumor antigen p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53l; bfy; bhy |
Gene, Accession # | TP53, Gene ID: 7157, SwissProt: P04637 |
Catalog # | abx000509 |
Price | |
Order / More Info | TP53 (pS315) Antibody from ABBEXA |
Product Specific References | n/a |
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