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Antigenic Specificity | Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (aa 721-735), (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RPS6KA1(Ribosomal Protein S6 Kinase, 90-KD, 1), also called RSK1, is an enzyme that in humans is encoded by the RPS6KA1 gene. The RSK(ribosomal S6 kinase) family comprises growth factor-regulated serine/threonine kinases, known also as p90(rsk). Homologs of RSK exist in several species. By analysis of somatic cell hybrids, Moller et al.(1994) mapped the RPS6KA1 gene to chromosome 3.Bonni et al.(1999) characterized the mechanism by which the RAS-MAPK signaling pathway mediates growth factor-dependent cell survival. Inoue et al.(2007) demonstrated that p90rsk, the kinase immediately downstream from Mos-MAPK, directly targets Erp1 for CSF arrest in Xenopus oocytes. |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human RSK1 p90(721-735aa ILAQRRVRKLPSTTL), identical to the related rat and mouse sequences. |
Other Names | Rsk1|p90rsk|rsk|HU-1|MAPKAPK1A|RSK|RSK1|RPS6KA|hu-1|mapkapk1a|rsk1|CLS|HU-3|ISPK-1|MAPKAPK1B|MRX19|RSK2|S6K-alpha3|p90-RSK2|pp90RSK2 |
Gene, Accession # | Gene ID: 6195 |
Catalog # | ABIN1673536 |
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Order / More Info | Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 1 (RPS6KA1) (aa 721-735), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 10558990, 17410130 |
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