产品详情 |
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Antigenic Specificity | RRM2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB, IF/ICC, IP. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RRM2 Antibody is a Rabbit Polyclonal antibody against RRM2. Ribonucleotide reductase M2 subunit is one of two subunits that constitute ribonucleotide reductase, the enzyme that catalyzes the conversion of ribonucleotide 5'-diphosphates into 2'-deoxyribonucleotides, a rate-limiting step in the production of 2'-deoxyribonucleoside 5'-diphosphates (dNTP) required for DNA synthesis and repair that is required for DNA synthesis and repair [PMID:20825972, 19250552]. RRM2 is only expressed during the late G1/early S phase, and degraded in late S phase, and the activity of RNR, and therefore DNA synthesis and cell proliferation, is controlled during the cell cycle by the synthesis and degradation of RRM2 subunit. |
Immunogen | Recombinant protein of human RRM2. |
Other Names | R2; RR2M; Ribonucleotide Reductase Small Chain; Ribonucleotide Reductase Small Subunit; Rrm2; Rr2; Ribonucleoside-diphosphate reductase subunit M2 |
Gene, Accession # | RRM2, Gene ID: 6241, SwissProt: P31350 |
Catalog # | abx004031 |
Price | |
Order / More Info | RRM2 Antibody from ABBEXA |
Product Specific References | n/a |
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