| 产品详情 |
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| Antigenic Specificity | BCL10 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. This BCL10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-51 amino acids from the N-terminal region of human BCL10. |
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| Immunogen | Human BCL10. |
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| Other Names | B-cell CLL/lymphoma 10; B-cell lymphoma/leukemia 10; BCL10; CARD- containing molecule enhancing NF-kappa-B; CARD-like apoptotic protein; CED- 3/ICH-1 prodomain homologous E10-like regulator; CIPER; CLAP; Cellular homolog of vCARMEN; Cellular-E10; Mammali; Bcl-10; CARD-containing molecule enhancing NF-kappa-B; hCLAP; CED-3/ICH-1 prodomain homologous E10-like regulator; cCARMEN; c-E10; Mammalian CARD-containing adapter molecule E10; mE10; CARMEN |
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| Gene, Accession # | BCL10, SwissProt: O95999 |
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| Catalog # | abx025858 |
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| Price | |
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| Order / More Info | BCL10 Antibody from ABBEXA |
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| Product Specific References | n/a |
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