产品详情 |
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Antigenic Specificity | TIRAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | IHC. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TIRAP Antibody is a Rabbit Polyclonal antibody against TIRAP. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described. |
Immunogen | Recombinant protein of human TIRAP. |
Other Names | MAL; Toll/interleukin-1 receptor domain-containing adapter protein; TIR domain-containing adapter protein; Adaptor protein Wyatt; MyD88 adapter-like protein; MyD88-2; wyatt; BACTS1; TIRAP; Adapter protein wyatt; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; HGNC:17192; FLJ42305; Toll-interleukin 1 receptor (TIR) domain-containing adapter protein; Toll-inte |
Gene, Accession # | TIRAP, Gene ID: 114609, SwissProt: P58753 |
Catalog # | abx001586 |
Price | |
Order / More Info | TIRAP Antibody from ABBEXA |
Product Specific References | n/a |
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