产品名称 TEPP-46 from BIOVISION, INC.
产品货号 B2164-1
产品价格 现货询价,电话:010-67529703
产品规格 1 mg
产品品牌 BIOVISION, INC.
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Product NameTEPP-46
DescriptionTEPP-46 (ML-265) is a potent and selective PKM2 activator. TEPP-46 activates tumor-specific PKM2 (EC50 = 92 nM) by binding to the dimer-dimer interface between two subunits of PKM2 and inducing tetramerization, which is the most active form of the enzyme. In mice with A549 xenograft tumors, ML-265 displays good oral bioavailability with relatively low clearance, long half-life. MW: 372.5. Purity ≥98% by HPLC
Size1 mg
Concentrationn/a
Applicationsn/a
Other Names6-[(3-aminophenyl)methyl]-4,6-dihydro-4-methyl-2-(methylsulfinyl)-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one; CID-44246499,NCGC00186528, ML-265
Gene, Accession, CAS #CAS: 1221186-53-3
Catalog #B2164-1
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Order / More InfoTEPP-46 from BIOVISION, INC.
Product Specific Referencesn/a
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