| 产品详情 |
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| Antigenic Specificity | GRM1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GRM1 Antibody is a Rabbit Polyclonal antibody against GRM1. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. |
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| Immunogen | A synthetic peptide of human GRM1. |
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| Other Names | GRM1; GRM1A; mGlu1; GPRC1A; MGLUR1; SCAR13; MGLUR1A; Metabotropic glutamate receptor 1mGluR1 |
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| Gene, Accession # | GRM1, Gene ID: 2911, SwissProt: Q13255 |
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| Catalog # | abx002156 |
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| Price | |
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| Order / More Info | GRM1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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| 产品资料 |
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