产品名称 Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (aa 371-385), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1672935
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityNuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (aa 371-385), (C-Term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formatimmunogen affinity purified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionLXRA is a tissue-specific cofactor that permits RXRA to function as a potent 9cRA receptor with a distinct target gene specificity. It specifically interacts with RXRA in vivo to form a functional heterodimer in which RXRA is the ligand-binding subunit. Additionally, LXR activity is critical for physiologic lipid metabolism and transport. LXRs are endogenous inhibitors of atherogenesis and are targets for therapeutic intervention in cardiovascular disease. Furthermore, LXRs and their ligands are negative regulators of macrophage inflammatory gene expression. LXR is also found that as a transcriptional switch that integrates hepatic glucose metabolism and fatty acid synthesis. The LXR-IDOL-LDLR axis defines a complementary pathway to sterol response element-binding proteins for sterol regulation of cholesterol uptake.
ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human LXR alpha(371-385aa NVQDQLQVERLQHTY), identical to the related rat and mouse sequences.
Other NamesNR1H3|LXR-a|LXRA|RLD-1|AU018371|LXR|RLD1|Unr1|LXRalpha|LXR-alpha|im:7141239|wu:fd59b01|zgc:113339|zgc:158542
Gene, Accession #Gene ID: 10062,58852
Catalog #ABIN1672935
Price
Order / More InfoNuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3) (aa 371-385), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 7744246, 12193651, 12524534, 17187055, 19520913
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