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Product Name | Recombinant Human Terminal nucleotidyltransferase 4A (TENT4B) |
Description | Purity > 85% as determined by SDS-PAGE. MW: 79.3kDa. Full Length: 1-572aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Catalytic subunit of a TRAMP-like complex which has a poly (A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo (A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Doesn't need a cofactor for polyadenylation activity (in vitro). Plays a role in replication-dependent histone mRNA degradation, probably through terminal uridylation of mature histone mRNAs. May play a role in sister chromatid cohesion. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | PAP-associated domain-containing protein 5; Terminal uridylyltransferase 3; TUTase 3; Topoisomerase-related function protein 4-2; TRF4-2 |
Gene, Accession, CAS # | TENT4B, UniProt: Q8NDF8 |
Catalog # | RPC25909 |
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Order / More Info | Recombinant Human Terminal nucleotidyltransferase 4A (TENT4B) from BIOMATIK |
Product Specific References | n/a |
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