| 产品详情 |
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| Antigenic Specificity | LIMK1/2 (pT508/505) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Phospho-LIMK1/2 (Thr508/505) Antibody detects endogenous levels of LIMK1/2 only when phosphorylated at Threonine 508/505. There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. Two splice variant have been identified. |
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| Immunogen | n/a |
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| Other Names | kinase LIMK1; KIZ-1; LIM domain kinase 1; LIMK; LIMK-1; LIMK1/2 (Phospho-Thr508/505); LIMK1/2 (pT508/505) |
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| Gene, Accession # | LIMK1, Gene ID: 3984, SwissProt: P53667 |
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| Catalog # | abx011920 |
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| Price | |
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| Order / More Info | LIMK1/2 (pT508/505) Antibody from ABBEXA |
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| Product Specific References | n/a |
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