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| Product Name | HDDC3, 1-140aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT. HDDC3, also known as guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, contains an active site for ppGpp hydrolysis and a conserved His-Asp-box motif for Mn(2+) binding. Consistent with these structural data, HDDC3 efficiently catalyzes hydrolysis of guanosine 3',5'-diphosphate (ppGpp) both in vitro and in vivo. HDDC3 also suppresses SpoT-deficient lethality and RelA-induced delayed cell growth in bacteria. Recombinant human HDDC3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | Guanosine-3'5'-bis(diphosphate)-pyrophosphohydrolase MESH1, Guanosine-3',5'-bis(diphosphate)-pyrophosphohydrolase MESH1, MESH1, ppGpp |
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| Gene, Accession, CAS # | NP 940929 |
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| Catalog # | ATGP1267 |
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| Order / More Info | HDDC3, 1-140aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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