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| 产品名称：米贝拉地er CAS No::116644-53-2,Chemical name: (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2 yl)propyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetr ahydro-1-(1-methylethyl)-2-naphthalenyl methoxyacetoacetate dihydrochloride,FORMULA:C29H38FN3O3.2HCl | |
| 货号：pro_111729 产地：tocris 规格/价格：询价 | |
| 产品详细说明: | |
| Mibefradil dihydrochloride Cat No. 2198 | |
| Alternative Name: Ro 40-5967 Chemical Name: (1S,2S)-2-[2-[[3-(1H-Benzimidazol-2 | |
Biological Activity Ca2+ channel blocker with moderate selectivity for T-type Ca2+ channels displayng IC50 values of 2.7 μM and 18.6 μM for T-type and L-type channels respectively. Antihypertensive agent.
Technical Data
568.56
C29H38FN3O3.2HCl
Soluble to 50 mM in water and to 100 mM in DMSO
>98 %
Desiccate at RT
[116644-53-2]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis and MSDS.
Resources
Certificate of Analysis / MSDS
Certificate of Analysis:
Select another batch: 321
Material Safety Data Sheet:
Select another batch: 321
References Osterriederand Holck (1989)In vtro pharmacologic profile of Ro 40-5967, a novel Ca2+ channel blockerwith potent vasodilator but weak inotropic action J.Cardiovasc.Pharmacol. b>13754. Veniant et al (1991) Hemodynamic profile of Ro 40-5967 inconscious rats: comparison with diltiazem, verapamil, and amlodipine.J.Cardiovasc.Pharmacol. 18 Suppl 10 S55. Mehrke et al(1994) The Ca(++)-channel blocker Ro 40-5967 blocks differently T-type andL-type Ca++ channels.?J.Pharmacol.Exp.Ther. 271 1483.
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