RELA (pS536) Antibody is a Rabbit Polyclonal antibody against RELA (pS536). NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Target |
RELA (pS536) |
Reactivity |
Human |
Host |
Rabbit |
Clonality |
Polyclonal |
Tested Applications |
WB |
Recommended dilutions |
WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Immunogen |
Recombinant Protein. A phospho specific peptide corresponding to residues surrounding S536 of human RELA. |
Purification |
Affinity purified. |
Form |
Liquid |
Isotype |
IgG |
Conjugation |
Unconjugated |
Storage |
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Molecular Weight |
Calculated MW: 58 kDa/59 kDa/60 kDa Observed MW: 65 kDa |
Swiss Prot |
Q04206
|
GeneID |
5970
|
Gene Symbol |
RELA |
Concentration |
> 1 mg/ml |
Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
UNSPSC Code |
12352203 |
Availability |
Shipped within 5-10 working days. |
Note |
This product is for research use only. |