This purified monoclonal antibody, made against Human PAI-1, is inhibitory through the binding of a epitope located on the F-Helix of PAI-1. The PAI/MoAB complex is a substrate for target proteinases tPA and urokinase. Specific for both human and mouse. Suitable for use in ELISA.

References:

1. Bijnens, A.P. et al. J Biol Chem. 275:6375-6380 (2000)