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产品名称 2′,3′-Dideoxyinosine - LKT Labs
产品货号 D3214
产品价格 现货询价，电话：010-67529703
产品规格 1 mg 5 mg 25 mg
产品品牌 lktlabs
产品概述
产品详情 2′,3′-Dideoxyinosine

Description

2’,3’-Dideoxyinosine is a purine (guanosine) nucleoside analog that exhibits antiviral activity through the direct inhibition of reverse transcriptase. 2’,3’-Dideoxyinosine acts as a chain terminator and is one component of highly active antiretroviral therapy (HAART) regimens used in the treatment of HIV and AIDS. 2’,3’-Dideoxyinosine also inhibits the humoral immune response in vivo, targeting B lymphocytes.

Product Info

Cas No.

69655-05-6

Purity

≥98%

Formula

C10H12N4O3

Formula Wt.

236.23

Chemical Name

2',3'-Dideoxyinosine

IUPAC Name

9-[(2R,5S)-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one

Synonym

Didanosine, Dideoxyinosine, ddI, ddIno, Videx

Melting Point

160-163°C

Solubility

Soluble in DMSO, polyethylene glycol.

Appearance

White Crystal Powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

D3214 MSDS PDF

Info Sheet

D3214 Info Sheet PDF

Brochures

Antivirals Booklet

References

Ribera E, Tuset M, Martín M, et al. Characteristics of antiretroviral drugs. Enferm Infecc Microbiol Clin. 2011 May;29(5):362-91. PMID: 21531048.

Phillips KE, Munson AE. 2'3'-Dideoxyinosine inhibits the humoral immune response in female B6C3F1 mice by targeting the B lymphocyte. Toxicol Appl Pharmacol. 1997 Aug;145(2):260-7. PMID: 9266798.
产品资料