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产品名称 [Gln8]-Luteinizing Hormone Releasing Hormone, chicken - LKT Labs
产品货号 L8277
产品价格 现货询价，电话：010-67529703
产品规格 1 mg 2 mg 5 mg
产品品牌 lktlabs
产品概述
产品详情 [Gln8]-Luteinizing Hormone Releasing Hormone, chicken [Gln8]-Luteinizing Hormone Releasing Hormone, chicken
Product ID L8277
Cas No. 47922-48-5
Purity ≥95%
Unit SizeCostQuantityStock
1 mg $63.00 In stock
2 mg $107.00 Please Inquire
5 mg $189.00 Please Inquire
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Description

Luteinizing hormone-releasing hormone (LHRH or Gonadotropin-releasing hormone [GnRH]) is an endogenous peptide hormone that binds the GnRH receptor, stimulating secretion of reproductive hormones (such as luteinizing hormone [LH ] and follicle-stimulating hormone [FSH]) from the pituitary gland. Analogs of GnRH are clinically used to treat hormone-dependent diseases such as prostate and breast cancer, hyperplasia, and endometriosis.

Product Info

Cas No.

47922-48-5

Purity

≥95%

Formula

C54H71N15O14

Formula Wt.

1154.28

IUPAC Name

(2S)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[(2-amino-2-oxoethyl)carbamoyl]pyrrolidin-1-yl]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]-5-oxopyrrolidine-2-carboxamide

Synonym

LHRH, GnRH

Appearance

White to off white powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

L8277 MSDS PDF

Info Sheet

L8277 Info Sheet PDF

References

Limonta P, Manea M. Gonadotropin-releasing hormone receptors as molecular therapeutic targets in prostate cancer: Current options and emerging strategies. Cancer Treat Rev. 2013 Oct;39(6):647-63. PMID: 23290320.

Millar RP, Newton CL. Current and future applications of GnRH, kisspeptin and neurokinin B analogues. Nat Rev Endocrinol. 2013 Aug;9(8):451-66. PMID: 23817290.

Wu HM, Wang HS, Huang HY, et al. Gonadotropin-releasing hormone type II (GnRH-II) agonist regulates the invasiveness of endometrial cancer cells through the GnRH-I receptor and mitogen-activated protein kinase (MAPK)-dependent activation of matrix metalloproteinase (MMP)-2. BMC Cancer. 2013 Jun 20;13:300. PMID: 23786715.

Burel D, Li JH, Do-Rego JL, et al. Gonadotropin-releasing hormone stimulates the biosynthesis of pregnenolone sulfate and dehydroepiandrosterone sulfate in the hypothalamus. Endocrinology. 2013 Jun;154(6):2114-28. PMID: 23554453.
产品资料