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产品名称 5-Bromo-2′-Deoxyuridine - LKT Labs
产品货号 B6856
产品价格 现货询价，电话：010-67529703
产品规格 250 mg 500 mg 1 g 5 g
产品品牌 lktlabs
产品概述
产品详情 5-Bromo-2′-Deoxyuridine 5-Bromo-2′-Deoxyuridine
Product ID B6856
Cas No. 59-14-3
Purity ≥98%
Unit SizeCostQuantityStock
250 mg $33.10 In stock
500 mg $55.10 In stock
1 g $82.70 In stock
5 g $325.30 In stock
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Description

5-Bromo-2’-deoxyuridine is a synthetic nucleoside analog of thymidine that is used in research models to label actively proliferating cells. This compound is incorporated into DNA but at low levels does not alter DNA replication. At high levels, this compound displays immunosuppressive activity and has shown some anticancer benefit when used as a chemotherapy radiosensitizer.

Product Info

Cas No.

59-14-3

Purity

≥98%

Formula

C9H11BrN2O5

Formula Wt.

307.11

Chemical Name

5-Bromo-2'-deoxyuridine

IUPAC Name

5-bromo-1-[(2R,4S, 5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

Synonym

Broxuridine, 5-bromouracil deoxyriboside, BUdR, Broxine, Neomark, Radibud

Melting Point

187-189°C

Solubility

Soluble in dimethyl- acetamide, 1N NaOH, or DMSO. Slightly soluble in water.

Appearance

White crystalline powder

Shipping and Storage

Store Temp

-20°C

Ship Temp

Ambient

Downloads

MSDS

B6856 MSDS PDF

Info Sheet

B6856 Info Sheet PDF

References

Zhang R, Zhang J, Fang L, et al. Neuroprotective effects of sulforaphane on cholinergic neurons in mice with Alzheimer's disease-like lesions. Int J Mol Sci. 2014 Aug 18;15(8):14396-410. PMID: 25196440.

Jeong CH, Kim SM, Lim JY, et al. Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model. Biomed Res Int. 2014;2014:129145. PMID: 24672780.

Russo A, Gianni L, Kinsella TJ, et al. Pharmacological evaluation of intravenous delivery of 5-bromodeoxyuridine to patients with brain tumors. Cancer Res. 1984 Apr;44(4):1702-5. PMID: 6704976.
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