产品名称 5-Fluorocytosine - LKT Labs
产品货号 F4581
产品价格 现货询价,电话:010-67529703
产品规格 500 mg 1 g 10 g 5 g
产品品牌 lktlabs
产品概述
产品详情 5-Fluorocytosine 5-Fluorocytosine
Unit SizeCostQuantityStock
500 mg $44.10 In stock
1 g $77.20 In stock
10 g $358.40 In stock
5 g $297.70 In stock

Description

5-Fluorocytosine, or Flucytosine, is a synthetic fluorinated pyrimidine analog that is used as an antifungal agent. In the presence of the enzyme cytosine deaminase it is converted to 5-fluorouracil, an antimetabolite that is an inhibitor of thymidylate synthase.

Product Info

Cas No.

2022-85-7

Purity

≥98%

Formula

C4H4FN3O

Formula Wt.

129.09

Chemical Name

6-amino-5-fluoro-2(1H)-pyrimidinone

IUPAC Name

4-Amino-5-fluoro-2(1H)-pyrimidinone

Synonym

Flucytosine, Ancobon, Ancotil, 5-FC, NSC 103805, Ro 2-9915

Solubility

Soluble in water (1.5 g/100 mL or 0.089 M).

Shipping and Storage

Store Temp

4°C

Ship Temp

Ambient

Downloads

MSDS

F4581 MSDS PDF

Info Sheet

F4581 Info Sheet PDF

References

Huang TT, Parab S, Burnett R, et al. Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model. Hum Gene Ther. 2015 Feb; 26(2):82-93. PMID: 25419577.

Davoudi N, Khamesipour A, Mahboudi F, McMaster WR. A dual drug sensitive L. major induces protection without lesion in C57BL/6 mice. PLoS Negl Trop Dis. 2014 May 29; 8(5):e2785. PMID: 24873970.

O’Connor L, Livermore J, Sharp AD, et al. Pharmacodynamics of liposomal amphotericin B and flucytosine for cryptococcal meningoencephalitis: safe and effective regimens for immunocompromised patients. J Infect Dis. 2013 Jul 15; 208(2):351-361. PMID: 23599314.

产品资料