Description

The collection of whole blood is the first step in many molecular assays used to study intracellular RNA. A major challenge in this type of testing is the instability of intracellular RNA, which rapidly degrades within hours after blood collection. Furthermore, certain species of RNA, through the process of gene induction, increase in vitro after blood collection. Both in vitro RNA degradation and gene induction can lead to an under- or over-estimation of in vivo relative gene transcript number.

The PAXgene™ Blood RNA Tube contains an additive that stabilizes the in vivo gene transcription profile by reducing in vitro RNA degradation and minimizing gene induction. When used in conjunction with the PAXgene™ Blood RNA Kit, the Blood RNA Tube provides for accurate detection and quantitation of gene transcripts. Store unused PAXgene Blood RNA Tubes at 18–25°C. (Limited excursion temperatures up to 40°C are permitted.)