Description

• Genetically inherited diseases in humans can be caused by a single nucleotide mutation resulting in a change. Such a substitution can affect the structure and function of a critical protein, rendering it partially or completely nonfunctional. A classic example is hemoglobin in sickle cell anemia
• Agarose gel-based experiment designed for DNA staining and visualization with InstaStain™ Methylene Blue
• Demonstrates the use of a restriction enzyme that discriminates between the normal and sickle cell hemoglobin genes
• This experiment does not contain human DNA