产品名称 Dimethylacrylshikonin | Biorbyt
产品货号 orb389963
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name Dimethylacrylshikonin
Catalog Number orb389963
ConjugationUnconjugated
Hazard InformationNon-Toxic
Target Dimethylacrylshikonin
Form/Appearance Powder
Storage Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months at 2-8°C.
Note For research use only.
Purity >98%
Formula C21H22O6
MW 370.39
CAS Number [24502-79-2]
Source The roots of Lithosperraum erythrorhizon Sieb. et Zucc.
Activity 1. Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors.
(a) Injection of Dimethylacrylshikonin combined with IR treatment significantly suppressed tumor growth of the HCT-116 xenograft.
(b) Dimethylacrylshikonin significantly suppressed the growth of H(22) transplantable hepatoma, and induced the activation of caspase-3 .
(c) Dimethylacrylshikonin inhibited growth of gastric cancer SGC-7901 cells by inducing ERK signaling pathway.
2. Dimethylacrylshikonin inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-kappaB pathway.
Application Notes Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
产品资料