产品名称 | Dimethylacrylshikonin | Biorbyt |
产品货号 | orb389963 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | |
产品品牌 | Biorbyt |
产品概述 | |
产品详情 | |
Product Name | Dimethylacrylshikonin |
---|---|
Catalog Number | orb389963 |
Conjugation | Unconjugated |
Hazard Information | Non-Toxic |
Target | Dimethylacrylshikonin |
Form/Appearance | Powder |
Storage | Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months at 2-8°C. |
Note | For research use only. |
Purity | >98% |
Formula | C21H22O6 |
MW | 370.39 |
CAS Number | [24502-79-2] |
Source | The roots of Lithosperraum erythrorhizon Sieb. et Zucc. |
Activity | 1. Dimethylacrylshikonin is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significantly suppressed tumor growth of the HCT-116 xenograft. (b) Dimethylacrylshikonin significantly suppressed the growth of H(22) transplantable hepatoma, and induced the activation of caspase-3 . (c) Dimethylacrylshikonin inhibited growth of gastric cancer SGC-7901 cells by inducing ERK signaling pathway. 2. Dimethylacrylshikonin inhibits the proliferation of MCF-7 cells in vitro by inducing apoptosis through the downregulation of Bcl-2, upregulation of Bax and partial inactivation of the NF-kappaB pathway. |
Application Notes | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
产品资料 |