产品名称 Complement C1q antibody
产品货号 orb25702
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name Complement C1q antibody
Catalog Number orb25702
Species/Host Sheep
Conjugation Unconjugated
Tested applications RID
Immunogen Human C1q
Target Complement C1q. Gives a single arc when tested by IEP against fresh human plasma. Identity has been confirmed bydouble diffusion Ouchterlony against fresh human plasma and a known anti human C1q. C1q is a subcomponentof the first complement component C1, which is formed by the interaction of C1q with thetetramer C1s C1r C1r C1s. C1q is a member of a family of soluble collagen like proteins and iscomposed of three basic subunits termed A, B and C 27,550, 25,200, 23,800 Da respectively whichassociate in the proportion 6 A B subunits 52,750 Da and 3 C C subunits 47,600 Da, to form wholeC1q 459,300 Da. C1q binds to IgG and IgM immune complexes, this activates C1r and C1s, whichare also bound to C1q and so initiates the classical pathway of complement activation. The normalplasma concentration of C1q is 100 180 mg/L.
Alternative Names
Form/Appearance Glycine Buffered Saline, pH 7.4
Concentration 14.98 mg/ml (OD280nm, E1%=14.5)
Preservatives 0.099% Sodium Azide, 0.1% EACA, 0.01% Benzamidine, 1 mm EDTA
Storage Store at -2 to -8°C.Slight precipitation can occur on storage which may be removed by centrifugation, andshould not affect performance characteristics.
Note For research use only.
Clonality Polyclonal
Purity Antiserum is adsorbed to monospecificity using solid-phase adsorbents. The titer of the immunoglobulinfraction is adjusted so that inter-batch variation is within 10%.Product is 0.2 um filtered.
Biological Origin Sample obtained from Goat.
Application Notes Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
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