| 产品名称 |
CD11/CD18 antibody | anti CD11/CD18 antibody | Biorbyt |
| 产品货号 |
orb223662 |
| 产品价格 |
现货询价，电话：010-67529703
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| 产品规格 |
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| 产品品牌 |
Biorbyt |
| 产品概述 |
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| 产品详情 |
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| Product Name |
CD11/CD18 antibody |
| Catalog Number |
orb223662 |
| Species/Host |
Mouse |
| Reactivity |
Human |
| Conjugation |
Unconjugated |
| Tested applications |
FACS, ICC, IF, IP, RIA, WB |
| Immunogen |
Fibronectin-purified human monocytes |
| Target |
CD11/CD18. This antibody recognises integrin alpha L,M,X/Beta 2 (CD11/CD18). Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits which mediate cell-cell and cell-extracellular matrix attachments. Integrin beta2 (CD18) associates with integrin alpha L (CD11a) to form the leukocyte function-associated antigen-1 (LFA-1) with integrin alpha M (CD11b) to form Complement Receptor 3 (CR3) and with integrin alpha X (CD11c) to form Complement Receptor 4 (CR4). Each integrin receptor can bind various Intercellular adhesion molecules (ICAMs). Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. |
| Alternative Names |
(click to expand)
anti Integrin alpha (L antibody, anti M antibody)/beta 2 antibody
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| Form/Appearance |
Phosphate buffered saline (PBS) containing 0.09% Sodium azide |
| Concentration |
1 mg/ml |
| Storage |
Store at 4°C for short term and at -20°C for long term storage |
| Note |
For research use only. |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Purity |
Purified on protein A from tissue culture supernatant. |
| Clone ID |
24 |
| Uniprot ID |
P20701 (Human) |
| Entrez |
3683 |
| Dilution Range |
Optimal antibody dilution should be determined by titration. |
| 产品资料 |
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