| 产品名称 | KRT8 antibody | anti KRT8 antibody | Biorbyt |
| 产品货号 | orb534712 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | Biorbyt |
| 产品概述 | |
| 产品详情 | |
| Product Name | KRT8 antibody |
|---|---|
| Catalog Number | orb534712 |
| Species/Host | Mouse |
| Reactivity | Bovine, Human, Porcine, Rabbit, Sheep |
| Conjugation | Unconjugated |
| Tested applications | IHC-P |
| Immunogen | Recombinant full-length human KRT8 protein |
| Target | Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ( ring-like, perinuclear ) from ductal ( peripheral-predominant ) carcinoma of the breast. |
| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
| Note | For research use only. |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Purity | Purified Ab with BSA and Azide at 200ug/ml |
| MW | 52.5 kDa |
| Clone ID | rB22.1 |
| Uniprot ID | P05787 |
| Entrez | 3856 |
| Dilution Range | IHC-P: 0.5-1.0 μg/ml for 30 min at RT |
| 产品资料 |