| 产品名称 | DES antibody | anti DES antibody | Biorbyt |
| 产品货号 | orb534579 |
| 产品价格 | 现货询价,电话:010-67529703 |
| 产品规格 | |
| 产品品牌 | Biorbyt |
| 产品概述 | |
| 产品详情 | |
| Product Name | DES antibody |
|---|---|
| Catalog Number | orb534579 |
| Species/Host | Rabbit |
| Reactivity | Gallus, Hamster, Human, Rat |
| Conjugation | Unconjugated |
| Tested applications | IHC-P |
| Immunogen | Recombinant full-length human DES protein |
| Target | Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain α-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. |
| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
| Note | For research use only. |
| Isotype | IgG |
| Clonality | Monoclonal |
| Purity | Purified Ab with BSA and Azide at 200ug/ml |
| MW | 52 kDa |
| Clone ID | DES/2960R |
| Uniprot ID | P17661 |
| Entrez | 1674 |
| Dilution Range | IHC-P: 1-2 μg/ml for 30 minutes at RT |
| 产品资料 |