| 产品名称 | CDC2 antibody | anti CDC2 antibody | Biorbyt |
| 产品货号 | orb535045 |
| 产品价格 | 现货询价,电话:010-67529703 |
| 产品规格 | |
| 产品品牌 | Biorbyt |
| 产品概述 | |
| 产品详情 | |
| Product Name | CDC2 antibody |
|---|---|
| Catalog Number | orb535045 |
| Species/Host | Mouse |
| Reactivity | Gallus, Guinea pig, Human, Mouse, Rat, Rodent, Xenopus |
| Conjugation | Unconjugated |
| Tested applications | IF, IHC-P, IP, WB |
| Immunogen | C-Terminal 2/3rds of Xenopus cdc2 expressed in E.coli |
| Target | Recognizes a 34kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins. |
| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
| Note | For research use only. |
| Isotype | IgG2a, kappa |
| Clonality | Monoclonal |
| Purity | Purified Ab with BSA and Azide at 200ug/ml |
| MW | 34 kDa |
| Clone ID | A17.1.1 |
| Uniprot ID | P06493 |
| Entrez | 983 |
| Dilution Range | IF: 1-2 μg/ml , IP: 2-4 μg/mg protein, WB: 0.5-1.0 μg/ml, IHC-P: 2-4 μg/ml for 30 minutes at RT |
| 产品资料 |