产品名称 CDC2 antibody | anti CDC2 antibody | Biorbyt
产品货号 orb535045
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name CDC2 antibody
Catalog Number orb535045
Species/Host Mouse
Reactivity Gallus, Guinea pig, Human, Mouse, Rat, Rodent, Xenopus
Conjugation Unconjugated
Tested applications IF, IHC-P, IP, WB
Immunogen C-Terminal 2/3rds of Xenopus cdc2 expressed in E.coli
Target Recognizes a 34kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins.
Form/Appearance 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Note For research use only.
Isotype IgG2a, kappa
Clonality Monoclonal
Purity Purified Ab with BSA and Azide at 200ug/ml
MW 34 kDa
Clone ID A17.1.1
Uniprot ID P06493
Entrez 983
Dilution Range IF: 1-2 μg/ml , IP: 2-4 μg/mg protein, WB: 0.5-1.0 μg/ml, IHC-P: 2-4 μg/ml for 30 minutes at RT
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