产品名称 |
CDC2 antibody | anti CDC2 antibody | Biorbyt |
产品货号 |
orb535045 |
产品价格 |
现货询价,电话:010-67529703
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产品规格 |
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产品品牌 |
Biorbyt |
产品概述 |
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产品详情 |
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Product Name |
CDC2 antibody |
Catalog Number |
orb535045 |
Species/Host |
Mouse |
Reactivity |
Gallus, Guinea pig, Human, Mouse, Rat, Rodent, Xenopus |
Conjugation |
Unconjugated |
Tested applications |
IF, IHC-P, IP, WB |
Immunogen |
C-Terminal 2/3rds of Xenopus cdc2 expressed in E.coli |
Target |
Recognizes a 34kDa protein (cdk1), identified as p34cdc2 (a catalytic subunit of Maturation Promoting Factor). Its epitope maps near the C-terminus of the protein and its core is thought to be LGTPNNEV (aa220-227 in murine cdc2). It shows no cross reaction with cdk2 p32. It supports the kinase activity. p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is a serine/threonine kinase, which is activated by cyclin, by dephosphorylation of tyrosine residues. p34cdc2 is inactivated by a tyrosine kinase. This MAb reportedly inhibits the activation of p34cdc2 kinase by cyclins. |
Form/Appearance |
10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Storage |
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
Note |
For research use only. |
Isotype |
IgG2a, kappa |
Clonality |
Monoclonal |
Purity |
Purified Ab with BSA and Azide at 200ug/ml |
MW |
34 kDa |
Clone ID |
A17.1.1 |
Uniprot ID |
P06493 |
Entrez |
983 |
Dilution Range |
IF: 1-2 μg/ml , IP: 2-4 μg/mg protein, WB: 0.5-1.0 μg/ml, IHC-P: 2-4 μg/ml for 30 minutes at RT |
产品资料 |
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